February 2018 Vol. 6 No.2

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Taechowisan T
Phutdhawong WS

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Original Research Article

Antifungal Activity of Biphenyls from Streptomyces sp. BO07 against Selective Phytopathogenic Fungi of Rice

Thongchai Taechowisan^1*, Suchanya Chaiseang¹ and Waya S. Phutdhawong²

¹Department of Microbiology, Silpakorn University, Nakorn Pathom 73000, Thailand
²Department of Chemistry, Faculty of Science, Silpakorn University, Nakorn Pathom 73000, Thailand

*Corresponding Author’s E-mail: tewson84@gmail.com
Tel: 66-34-245337, Fax: 66-34-245336
 
Accepted January 13, 2018

Abstract

The antifungal effect of two biphenyl compounds, 3'-hydroxy-5-methoxy-3,4-methylenedioxybiphenyl (1) and 3'-hydroxy-5,5'-dimethoxy-3,4-methylene-dioxybiphenyl (2) against phytopathogenic fungi of rice; Bipolaris oryzae, Fusarium semitectum, Fusarium fujikuroi and Curvularia lunata was analyzed. Results of this study showed that compound 1 and 2 exhibited a very strong inhibitory activity against tested fungi with minimum inhibitory concentration (MIC) values of ≤128 g/ml. Treatment with these compounds inhibited fungal radial growth, biomass formation, and spore density. The growth inhibition resulted from these compounds is due to the lysis of fungal cells indicated by the size of mycelia, in which the size of mycelia treated with these compounds is obviously smaller than that of control.

Keywords: Antifungal activity, Biphenyls, Phytopathogenic fungi, Rice