March 2014 Vol. 2 No. 2

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Full Length Research Paper

Agreement and Discrepancy between Optical Coherence Tomography and Fundal Fluorescein Angiography in Detection of Macular Edema
 

Mahgoub Saleem* and Mawahib Ibrahim, MD
 

Associate Professor, Faculty of Medicine, Al Neelain University Khartoum 11111, P. O. Box 10139, Sudan

*Corresponding Author's E-mail: saleem4eyes@gmail.com

Accepted March 24, 2014

Abstract

Macular edema (ME) is a common cause of a sudden or chronic decrease in visual acuity. It refers to accumulation of fluids within the retinal macular layers due to pathological disruption in the normal blood-retinal barrier (BRB). To determine the agreement and discrepancy between the Optical Coherence Tomography (OCT) and Fundus Fluorescein Angiography (FFA) in detection of Macular Edema (ME) of deferent causes. In a prospective, descriptive cross sectional study over a 6 month period at Makkah Eye Complex (MEC) Retina clinic, Diabetic Eye Clinic and Ophthalmic Investigation Department. Interpretation of OCTs and FFAs images was done for consecutive 252 eyes that had undergone FFA and OCT simultaneously to rule out ME. Of 252 eyes, 232 eyes (92.1%) had the finding of ME confirmed by both techniques. There were 8 eyes (3%) for which FFA showed dye leakage in the macular area and OCT showed normal foveal contour and no intraretinal edema. For 12 eyes in the study (5%), OCT showed intraretinal and subretinal fluid, which was not detected by FFA. Both FFA and OCT are highly sensitive techniques and correlate well in detection of ME. However, there is a small chance that when performed alone they might miss existing subtle ME.

Keyword: Blood-retinal barrier, Fundal Fluorescein Angiography, Optical Coherence Tomography Macular Edema, Intraretinal fluid, Subretinal fluid.