October 2018 Vol. 6 No.10

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Review

Risk Factors for Cervical HPV Infection

Ioannis Thanasas^1*, Giagkos Lavranos², Penelopi Gogou³, Konstantinos Tsioutis² and Dimitrios Paraskevis⁴

¹Department of Obstetrics & Gynecology of General Hospital in Trikala, Trikala, Greece
²Medical School and Department of Health Sciences, European University Cyprus
³Clinical Oncology Department, Norwich University Hospital, UK
⁴Department of Hygiene Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece

*Corresponding Author’s E-mail: thanasasg@hotmail.com
Phone: 2431029103 / 6944766469

Accepted October 10, 2018

Abstract

Human papillomavirus (HPV) infection is known to cause a subset, although not sufficient, of cervical cancer. In this article, we review current data and synthesize evidence on major risk factors associated with cervical HPV infection. A descriptive analysis of etiology and pathogenesis of the HPV infections is contributed in recognizing all the important determinants risks. A model that categorizes the viral genetic factors, as well as, the role of host genes and environmental factors in the pathogenesis of HPV infection is the only way to identify the biological mechanism of pathogenesis. Awareness of risk factors, are vital to achieving improved outcomes for patients with this increasingly prevalent cervical HPV infection.

Keywords: HPV, HPV cervical infection, cervical cancer, risk factors