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April 2017 Vol. 5 No.4

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Fahad A

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Merit Research Journal of Medicine and Medical Sciences (ISSN: 2354-323X) Vol. 5(4) pp. 197-201, April, 2017

Case Report

Hemophagocytic lymphohistiocytosis (HLH): Case Report

Fahad AlAmr

Department of pediatrics, Maternity and Children Hospital, Dammam, KSA

Email: fahadamr9@gmail.com

Accepted April 15, 2017

Abstract

Hemophagocytic lymphohystiocytosis (HLH) represents a severe hyper-inflammatory condition with the cardinal symptoms prolonged fever, hepatosplenomegaly, and cytopenias. The most prominent histopatho-logical feature of HLH is an accumulation of activated T lymphocytes and macrophages predominantly in lymphoid tissues. Although it can occur in all age groups, neonatal-onset HLH is very rare. The present study reported a case of HLH presenting with anemia and hepatosplenomegally at age of two month.

Keywords: Hemophagocytic lymphohistiocytosis, neonatal-onset.