October 2020 Vol. 8 No.10

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Case Report

Two-Year Study of a Case of Medication-Related Osteonecrosis of the Lower Jaw Treated With Platelet-Rich Fibrin

Rosen Tsolov^1*, Georgi Yordanov²

¹Department of maxillo-facial surgery, University Hospital “St. Georgi”, Medical University of Plovdiv
²Department of Radiology, Dental Allergology and Physiotherapy”, Faculty of Dental Medicine, Medical University of Plovdiv

*Corresponding Author Email: dr.rosentsolov@gmail.com

Received: 03 October 2020  I  Accepted: 20 October 2020  I  Published: 23 October 2020  I  Article ID: MRJMMS-20-168
Copyright © 2020 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0.

Abstract

Osteonecrosis of the jaw (MRONJ) is associated with the consequences of taking antiresorptive or antiangiogenic medicine for bone metastases or osteoporosis. MRONJ is characterized by open necrotic bone in the maxillofacial area that lasts more than eight weeks. The management of such a condition depends on several factors, among which the choice of MRONJ therapeutic method is considered to be the leading one. However, to date, no specific treatment with a uniform standard of treatment has been established. The purpose of this article is to present the outcome of surgical treatment of MRONJ with the addition of platelet-rich fibrin (PRF). A case of a woman with Medication-related osteonecrosis of the lower jaw, whose condition was monitored for a period of two years, is presented.

Keywords: Innovative method, Lower jaw, PRF, MRONJ, Osteonecrosis, Open necrotic bone