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MERIT RESEARCH JOURNAL OF MEDICINE AND MEDICAL SCIENCES (MRJMMS) (ISSN: 2354-323X)

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February 2018 Vol. 6 No.2

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Akgun FS
Ates O

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Merit Research Journal of Medicine and Medical Sciences (ISSN: 2354-323X) Vol. 6(2) pp. 068-072, February, 2018

Original Research Article

Systematic Evaluation of Adverse Reactions That May Occur After Injection of Type-A Botulinum Toxin in Patients with Spasmodic Torticollis Admitted to Emergency Department

Feride Sinem AKGUN^1*, Numan KARAARSLAN², Ibrahim YILMAZ³, Hanefi OZBEK⁴, Tezcan CALISKAN² and
Ozkan ATES⁵

¹Assist. Prof. M.D., Maltepe University School of Medicine, Department of Emergency, 34843, Istanbul, Turkey
²Assist. Prof. M.D., Namik Kemal University School of Medicine, Department of Neurosurgery, 59100, Tekirdag, Turkey.
³Medical Pharmacologist, pharmacist, Istanbul Medipol University School of Medicine, Department of Medical Pharmacology, 34810, Istanbul, Turkey.
⁴Prof. M.D., Ph.D., Istanbul Medipol University School of Medicine, Department of Medical Pharmacology, 34810, Istanbul, Turkey.
⁵Prof. M.D., Istanbul Esenyurt University, Esencan Hospital, Department of Neurosurgery, 34517, Istanbul, Turkey.

*Corresponding Author’s É-mail: bfsakgun@hotmail.com
Phone: +9021 6444 0620
Fax: +9021 6383 0274

Accepted February 21, 2018

Abstract

Type-A botulinum toxin (BTX-A) is today frequently used for cosmeceutical purposes. In addition, it is used extensively in the treatment of the patients with spasmodic torticollis in neurosurgery practice. However, patients admitted to the emergency department with adverse reactions / adverse events observed, especially after these applications constitute a severe problem. In this study, it was aimed to systematically evaluate the adverse reactions or events reported in the literature after administering BTX-A injections to the patients with spasmodic torticollis between Nov-1-1997 and Feb-13-2018. The data obtained from this research, it will be able to be seen a bigger image about these negativities that may arise. Thus, the management strategies for the treatment of such cases admitted to emergency departments can be planned more easily.

Keywords: Adverse reactions, Adverse events, Spasmodic torticollis, Type-A botulinum toxin injections