September 2016 Vol. 4 No.9

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Original Research Article

Evaluation of Iron, Copper, Manganese, Nickel and Zinc Levels in Serum of Patients Underwent to Different Surgical and Non Surgical Strategies to Reduce Weight

Ahssan Ali Lefta and ^*Rasha Hasan Jasim

Department of Chemistry-Faculty of Education for Girls-University of Kufa-Iraq

*Corresponding Author’s E-mail: dr.rashahussainee@yahoo.com

Accepted September 05, 2016

Abstract

Every day, life requires levels of high physical activity and food, the tendency genetic prefer to store excess calories in order to help the body to stay alive, so an overweight means increase in the body weight compared with the level of weight acceptable to the normal. Its belief that obesity is a result for losing of ability to correct habits of eating. Obesity is not a single disease, there are 300 different genes that were linked to obesity, in addition to several environmental factors could be associate to obesity happening, while most considerations commonly indicted to the fact that obesity process is a result of an interaction of environmental factors with the genetic predisposition lead to fat accumulation and increased in the adipose tissues. Trace elements are important materials for biochemical reactions in the human body. They are intervening in the synthesis of hormones, reproduce the cells, the immune system, and food digestion. Elements are inorganic compounds, do not synthesis in the body and are contain a minimum amount, so they are necessary for consumption food as well as more important in human life. 47patients (33.28 ±7.424 years with age range 34 years) and 24 healthy individuals (25.96 ± 3.983 years with age range 13 years) were enrolled in the present study. Patients with BMI more than 30 Kg/m² (45.179 ± 9.09 Kg/m², and 38.7 Kg/m² as BMI range); haven’t diabetes mellitus, they aren’t subjected to obesity surgical operation before. Control group might at approximate age range with the patients group, with similar food style. Average BMI of no smoking, no alcohol drinking healthy group was 18.5 Kg/m² (22.829 ± 0.752 Kg/m²). A significant (p < 0.05) decrease of the Fe, Cu, Mn, and Ni levels in the patients’ group comparison to those of healthy individuals. Results of Zn came unfamiliar to other element so as previous obesity studies, no significant variation (p > 0.05) was recorded when Zn levels of healthy and patients groups were compared together. Levels of Fe at obese patients were correlated significantly to Cu, Mn and Ni, while in the control group similar correlations were indicated at Fe to Cu and Mn levels only, on the other hand, level of Ni at healthy group failed to illustrate same patients results when it correlated to Fe. Strong positive correlation was observed for decreasing of Ni and Mn levels at patients group, in contrast to the relationship at the levels of these elements at control group which stay uncorrelated. Moderate significant correlation was noted at Ni and Zn levels were compared together at obese patients group, while no such correlation was observed at control individuals group. Other correlations were not statistical significance either at the neither healthy individuals nor obese patients. At obese group, statistical analysis showed that gender had no effect in the levels of the studies elements, except Mn and Ni. Although levels of Mn and Ni at the obese women were less than those in the control women, but these levels were higher than that recorded at obese males. In the control group, results of the advised trace elements didn’t show significant differences between female and male subgroups. Evaluated trace elements in the current study at male patients were less than those noted at obese females. Zn levels don’t correlated to obese individuals unless they had been have health complications correlated to obesity. Ni may be consider as a new trace element could use in the assessment of obesity and follow up its complications.

Keywords: Bypass, obese, sleeve and balloon, surgical operation, trace elements