January 2015 Vol. 3 No. 1

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Short Communication

Anti anaemic and Nephrotoxic effect of ethanolic extract Eremomastax speciosa

^*1Iba Innocent Udofia, ¹Etuk Ekaete Uduakobong, ¹Akpanabiatu Monday Isaiah, ²Item Ekaidem and
¹Ekong Immaculata Nkereuwem

¹Department of Biochemistry, University of Uyo, Akwa Ibom State, Nigeria
²Department of Chemical Pathology, University of Uyo Teaching Hospital, Akwa Ibom State

*Corresponding Author's E-mail: innoscobmt@yahoo.com

Accepted October 07, 2014

Abstract

The ethanolic leaf extract of Eremomastax speciosa was evaluated for its anti-anaemic activity and it possible adverse effect on the Kidney function of Wistar albino rats. The effect of ethanolic extract on haemoglobin concentration, red blood cell count, packed cell volume, white blood cell count and platelet count was investigated. The extract 100 – 300 mgKg-1 demonstrated antianaemic property by significantly (p<0.05) increasing the levels of red blood cell count, haemoglobin level, packed cell volume and white blood cell counts of treated animals. The ethanolic extract of the plant also indicated no adverse effect on the kidney function by non- significantly increasing serum creatinine and urea levels.

Keywords: Anti-anaemic, Extract, Haemoglobin, Nephrotoxic, Platelet Counts