December 2015 Vol. 3 No.12

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Original Research Article

A comparative study of plasma uric acid, erythrocyte uric acid and urine uric acid levels in type 2 diabetic subjects

Nagendra S.¹, Yogaraje gowda C. V.² and Kashinath R. T.^3*

¹Associate Prof. Department of Medicine, Subbaiah Institute of Medical Sciences and Research Center, NH-13, Purle. Shimoga-577222
²Research Scholar, Dept of Biochemistry, Subbaiah Institute of Medical Sciences and Research Center,
NH-13, Purle. Shimoga-577222
³Prof. and HOD, Department of Biochemistry, Subbaiah Institute of Medical Sciences and Research Center NH-13, Purle. Shimoga-577222

*Corresponding Author’s E-mail: drkashinath_1945@yahoo.co.in

Accepted December 14, 2015

Abstract

In the recent past, uric acid, the end product of Purine metabolism in humans, has been claimed elevated in type 2 diabetic subjects, with a good correlation to diabetic complications. Uric acid is sparingly soluble in body fluids and information regarding its distribution in body fluids particularly blood and urine as well as in plasma and erythrocytes is scanty. A study was undertaken to assess the distribution of uric acid in type 2 diabetic subjects in plasma, erythrocytes and in urine. The results suggest there is an equal distribution and the urinary excretion is significantly reduced.

Keywords: Erythrocytes, Plasma, Type-2 Diabetes Mellitus, Uric acid, Urine.